Critical limb Ischemia is a blockage in the arteries that severely reduces the blood circulation to the lower limbs. It is a serious form of peripheral arterial disease, causing narrowing of the arteries and therefore a reduced blood flow to the limbs. Critical limb ischemia can cause pain in the legs, feet and toes and can result in sores that do not heal and the need for amputation.
Stem cells have the potential to self-generate themselves into many different cell types. Autologus stem cell therapy is when the patients own stem cells are used to treat the condition. Bone marrow stem cells are collected from the patient and then frozen and stored until they are needed.
The stem cells are then implanted back into the patient with the aim to repair and replace the affected blood vessels and arteries, therefore, increasing the blood circulation.